Owen Astrachan (Professor, Computer Science at Duke) invited a graduate of Duke, Ge Wang, to be a guest speaker to his Technical and Social Foundations of the Internet course (CS 82). Dr. Wang, at Stanford University, used Skype to connect with the 340 students at Duke, alternating between a video of himself talking, and sharing his computer screen for his presentation. 
Astrachan reported “it just worked” and was delighted with how easily he was able to share a guest speaker with his students.
After this was posted, Heidi Madden directed me to a video showing a Duke German history class using Skype to talk to photographer Vince Cianni about his original photographs of the fall of the Berlin wall. Join them by watching the video.